VB-Virus Block technology

The expectations for VB®
(Virus-Block) Series
There is a growing interest for hand hygiene to combat against common viruses such as Influenza, Rhino virus (common cold), Food-borne illnesses, and nosocomial infections.

Hands are the main pathways of germ transmission during our everyday life, e.g., money, hand rails, cell phones, doorknobs, etc.

Hand hygiene is therefore one of the most important measures to avoid the transmission of harmful germs and prevent various kinds of infections.
MPM compounds are the key to inhibit microbial activities.
MPM compounds are jointly-invented with a venture company consists of Tokyo Institute of Technology and Keio University
What are MPM compounds?
MPM compounds, through the course of study, have been proven to have promising medical applications. MPM compounds are a mixture of five biologically active components that deter microbiological activity. The integrity of each component is retained and the combination strengthens the effectiveness of the five components including the polyoxometalates (metal-oxide cluster substances), antibiotic and antimicrobial agents.

Antiviral

VB-Virus Block technology successfully and effectively combats viral activity.
VB Wet Wipe is 99.9% or more effective against virus activity compared to other wet wipes.
Even at approximately 100 degrees Celsius, VB Wet Wipe retains its anti-viral properties.
Test Results on MPM compounds VB soluton is the liquid version of MPM compounds.
■Result of Anti-RNA Viral Activity
Celluar virus development after influenza exposure
Testing Agency: Reserch organization of bioactivity
■Decreasing Effect of Viral Infectivity
Testing Agency: Reserch organization of bioactivity
■Anti-Influenza Viral Inactivation Test on Linen Towel (Dry Process)
Testing Agency: Reserch organization of bioactivity

Antibacterial

VB Wet Wipe is 90% more effective against general bacterial growth compared to other wet wipes.
■Result of Inhibition Against MRSA
MRSA (Methicillin-resistant Staphylococcus aureus) is a bacterium responsible for several difficult-to-treat infections in humans. Resistance does make MRSA infection more difficult to treat with standard types of antibiotics and thus more dangerous.
Test data by JFRL (Japan Food Research Laboratories)
■Result of Inhibition Against Bacillus Cereus
Bacillus cereus is a soil-dwelling, Gram-positive, rod-shaped, beta hemolytic bacterium, facultative anaerobe that is a well known cause of food-borne illnesses having a high resistance to heat and alcohol. VB Wet Wipe provides safe and efficient hand hygiene.
Test data by JFRL (Japan Food Research Laboratories)
■VB’s Inhibition Result Against bacteria proliferation
Right after opening Oshibori plastic bag, inhibition result of bacteria
1 week after opening Oshibori plastic bag, inhibition result of bacteria
Test data by JFRL (Japan Food Research Laboratories)

Deodorizing

VB Wet Wipe prevents offensive odor generation.
■Surface Inhibitory effect of MPM compounds against bacterial growth of opened Oshibori wet wipes
Testing Agency: Research organization of bioactivity

Safe

No oral toxicity or dermal irritancy. VB Wet Wipe provides safe and efficient hand hygiene even for sensitive skin and children.
■Safety Data Test Summary
●Acute Toxicity : cleared
No abnormal LD50>2g/kg (oral dose, rats)
●Subacute Toxicity : cleared
Oral administered continuously for 90 days for 10 rats. Applied Dosage: 1g/kg of VBR. Result: zero fatalities, morphological physical appearance noted
Test groups’ organs, upon autopsy after 90 days, were not nominal and reflected the control groups organ results.
●Local Effect : cleared
No skin sensitization was observed on skin sensitization test in marmots.
●Eye Irritation Test : cleared
No material facts to report for irritation on marmots and rats. Microscopic observance of red eyes annotated for one marmot, follow-up period the observance had disappeared. Observance was considered transient.
Testing Agency: Research organization of bioactivity
●Primary Skin Irritation Test in Rabbits: no irritation response was observed.
●Voluntary Standards for Wet Wipe Category created by JHPIA
(Japan Hygiene Products Industry Association):
Cleared
Testing Agency: JFRL (Japan Food Research Laboratories)
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